Endfolium sclerosis in temporal lobe epilepsy diagnosed preoperatively by 3-tesla magnetic resonance imaging: Case report

Masaki Iwasaki, Nobukazu Nakasato, Hiroyoshi Suzuki, Teiji Tominaga

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

A 34-year-old man presented with intractable temporal lobe epilepsy. Three-tesla magnetic resonance imaging revealed increased T2 signal intensity and volume loss limited to the CA4 region of the right hippocampus. A right anterior temporal lobectomy and amygdalohippocampectomy were performed. Histological examination of the hippocampus disclosed severe neuron loss limited to the CA4 region, consistent with the preoperative imaging, which is a pattern known as endfolium sclerosis. Close inspection of the internal hippocampal anatomy with high-field MR imaging is useful in patients with temporal lobe epilepsy, because endfolium sclerosis may be associated with less chance of seizure freedom after temporal lobectomy.

Original languageEnglish
Pages (from-to)1124-1126
Number of pages3
JournalJournal of neurosurgery
Volume110
Issue number6
DOIs
Publication statusPublished - 2009 Jun

Keywords

  • Endfolium sclerosis
  • Epilepsy surgery
  • Hippocampal sclerosis
  • Magnetic resonance imaging
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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