Encapsulating Peritoneal Sclerosis

Helen Alston, Stanley Fan, Masaaki Nakayama

Research output: Contribution to journalReview articlepeer-review

15 Citations (Scopus)


Encapsulating peritoneal sclerosis (EPS) is a rare but serious complication of peritoneal dialysis. In this review, we describe the clinical picture and histologic changes to the peritoneal membrane that are associated with EPS and provide an update on current diagnosis and management. We also discuss the recent studies that have suggested that the use of more biocompatible solutions containing lower concentrations of glucose degradation product that often are pH neutral in combination with a change in clinical practice (reducing glucose exposure and monitoring peritoneal membrane function) might ameliorate peritoneal degeneration, reduce the incidence of EPS, and minimize the severity of the disease.

Original languageEnglish
Pages (from-to)93-102
Number of pages10
JournalSeminars in Nephrology
Issue number1
Publication statusPublished - 2017 Jan 1


  • EPS
  • Encapsulating peritoneal sclerosis
  • peritoneal dialysis
  • peritoneal membrane

ASJC Scopus subject areas

  • Nephrology


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