Enantioselective total synthesis of litseaverticillols A and B

Akira Morita, Shigefumi Kuwahara

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


The first enantioselective total synthesis of the (1R,5S)-stereoisomer of litseaverticillols A and B, anti-HIV monocyclic sesquiterpenoids isolated from a perennial shrub found in Vietnam, was accomplished in six steps from homogeranic acid by employing the Evans asymmetric aldol reaction and a microwave-promoted cyclization of a stannylated thiol ester intermediate as the C-C bond-forming steps.

Original languageEnglish
Pages (from-to)1613-1616
Number of pages4
JournalOrganic letters
Issue number8
Publication statusPublished - 2006 Apr 13

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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