Enantioselective synthesis of the (1S,5R)-enantiomer of litseaverticillols A and B

Akira Morita, Hiromasa Kiyota, Shigefumi Kuwahara

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)

    Abstract

    An enantioselective synthesis of the (1S,5R)-enantiomer of litseaverticillols A and B was accomplished in line with our previously reported synthetic pathway for their (1R,5S)-enantiomer. The use of "EtSCeCl 2" prepared from EtSLi and CeCl3, instead of previously employed EtSLi itself, for the formation of thiol ester intermediates prevented any undesirable epimerization occurring in the process.

    Original languageEnglish
    Pages (from-to)2564-2566
    Number of pages3
    JournalBioscience, Biotechnology and Biochemistry
    Volume70
    Issue number10
    DOIs
    Publication statusPublished - 2006

    Keywords

    • Anti-HIV
    • Enantioselective synthesis
    • Litseaverticillol
    • Sesquiterpenoid

    ASJC Scopus subject areas

    • Biotechnology
    • Analytical Chemistry
    • Biochemistry
    • Applied Microbiology and Biotechnology
    • Molecular Biology
    • Organic Chemistry

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