Enantioselective synthesis of the (1S,5R)-enantiomer of litseaverticillols A and B

Akira Morita, Hiromasa Kiyota, Shigefumi Kuwahara

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

An enantioselective synthesis of the (1S,5R)-enantiomer of litseaverticillols A and B was accomplished in line with our previously reported synthetic pathway for their (1R,5S)-enantiomer. The use of "EtSCeCl 2" prepared from EtSLi and CeCl3, instead of previously employed EtSLi itself, for the formation of thiol ester intermediates prevented any undesirable epimerization occurring in the process.

Original languageEnglish
Pages (from-to)2564-2566
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume70
Issue number10
DOIs
Publication statusPublished - 2006

Keywords

  • Anti-HIV
  • Enantioselective synthesis
  • Litseaverticillol
  • Sesquiterpenoid

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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