(+)-Decarestrictine L has been synthesized in enantiomerically pure form from (3R,4S)-1-benzyloxy-6-heptene-3,4-diol, prepared from (2E,5E)-1,7- dibenzyloxy-2,5-heptadien-4-ol, employing either Me2AlCl promoted methylative cleavage of (1R,5R,6S)-6-benzyloxy-2,9-dioxabicyclo[3.3.1]nonane or DIBAH promoted reductive cleavage of (1R,5R,6S)-6-benzyloxy-1-methyl-2,9- dioxabicyclo[3.3.1]nonane for the construction of the substituted pyran ring system.
|Number of pages||4|
|Publication status||Published - 2000 Feb 1|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry