Enantioselective synthesis induced by chiral epoxides in conjunction with asymmetric autocatalysis

Tsuneomi Kawasaki; Masako Shimizu; Kenta Suzuki; Itaru Sato; Kenso Soai

doi:10.1016/j.tetasy.2004.09.036

Enantioselective synthesis induced by chiral epoxides in conjunction with asymmetric autocatalysis

Tsuneomi Kawasaki, Masako Shimizu, Kenta Suzuki, Itaru Sato, Kenso Soai

SCI - Research and Analytical Center for Giant Molecules

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

5-Pyrimidyl alkanol with an enantiomeric excess of up to 96% was formed using chiral epoxides as a chiral initiator in the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, in conjunction with asymmetric autocatalysis.

Original language	English
Pages (from-to)	3699-3701
Number of pages	3
Journal	Tetrahedron Asymmetry
Volume	15
Issue number	23
DOIs	https://doi.org/10.1016/j.tetasy.2004.09.036
Publication status	Published - 2004 Nov 29

ASJC Scopus subject areas

Catalysis
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.1016/j.tetasy.2004.09.036

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title = "Enantioselective synthesis induced by chiral epoxides in conjunction with asymmetric autocatalysis",

abstract = "5-Pyrimidyl alkanol with an enantiomeric excess of up to 96% was formed using chiral epoxides as a chiral initiator in the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, in conjunction with asymmetric autocatalysis.",

author = "Tsuneomi Kawasaki and Masako Shimizu and Kenta Suzuki and Itaru Sato and Kenso Soai",

note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research from The Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan.",

year = "2004",

month = nov,

day = "29",

doi = "10.1016/j.tetasy.2004.09.036",

language = "English",

volume = "15",

pages = "3699--3701",

journal = "Tetrahedron Asymmetry",

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TY - JOUR

T1 - Enantioselective synthesis induced by chiral epoxides in conjunction with asymmetric autocatalysis

AU - Kawasaki, Tsuneomi

AU - Shimizu, Masako

AU - Suzuki, Kenta

AU - Sato, Itaru

AU - Soai, Kenso

N1 - Funding Information: This work was supported by a Grant-in-Aid for Scientific Research from The Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan.

PY - 2004/11/29

Y1 - 2004/11/29

N2 - 5-Pyrimidyl alkanol with an enantiomeric excess of up to 96% was formed using chiral epoxides as a chiral initiator in the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, in conjunction with asymmetric autocatalysis.

AB - 5-Pyrimidyl alkanol with an enantiomeric excess of up to 96% was formed using chiral epoxides as a chiral initiator in the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, in conjunction with asymmetric autocatalysis.

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U2 - 10.1016/j.tetasy.2004.09.036

DO - 10.1016/j.tetasy.2004.09.036

M3 - Article

AN - SCOPUS:9644294209

VL - 15

SP - 3699

EP - 3701

JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

SN - 0957-4166

IS - 23

ER -

Enantioselective synthesis induced by chiral epoxides in conjunction with asymmetric autocatalysis

Abstract

ASJC Scopus subject areas

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