Enantioselective synthesis and stereochemical revision of communiols A-C

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7 Citations (Scopus)


Enantioselective synthesis of the proposed structure of communiol C, an antibacterial tetrahydrofuran derivative produced by Podospora communis, and its stereoisomers revealed that the genuine stereochemistry of communiol C should be 3R, 5R, and 6S. Two other structurally related metabolites of the same microbial origin, communiols A and B, were also synthesized based on the revised stereochemistry.

Original languageEnglish
Pages (from-to)6297-6300
Number of pages4
JournalTetrahedron Letters
Issue number37
Publication statusPublished - 2005 Sep 12


  • Antibacterial
  • Asymmetric dihydroxylation
  • Communiol
  • Enantioselective synthesis
  • Podospora communis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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