Enantioselective intramolecular cyclization of alkynyl esters catalyzed by a chiral Brønsted base

Azusa Kondoh, Hoa Thi Quynh Tran, Kyoko Kimura, Masahiro Terada

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

An enantioselective intramolecular cyclization reaction of alkynyl esters was developed, which employs a Brønsted base catalyst generated in situ from a chiral Schiff base and t-BuOK. This reaction is a rare example of the enantioselective intramolecular addition of simple ester enolates to alkynes under Brønsted base catalysis.

Original languageEnglish
Pages (from-to)5726-5729
Number of pages4
JournalChemical Communications
Volume52
Issue number33
DOIs
Publication statusPublished - 2016 Apr 28

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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