Enantioselective direct amination of α-cyanoacetates catalyzed by bifunctional chiral Ru and Ir amido complexes

Yasuharu Hasegawa, Masahito Watanabe, Ilya D. Gridnev, Takao Ikariya

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

The bifunctional chiral amido Ir complex catalyzed asymmetric electrophilic direct amination of α-substituted α-cyanoacetates using azodicarboxylates proceeds rapidly to provide the corresponding hydrazine adducts in high yields and with excellent ee values.

Original languageEnglish
Pages (from-to)2158-2159
Number of pages2
JournalJournal of the American Chemical Society
Volume130
Issue number7
DOIs
Publication statusPublished - 2008 Feb 20
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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