Abstract
A Pd(OAc)2-SEGPHOS combination catalyzes the first enantioseiective aryiative cyclization of allenyl aldehydes with aryiboronic acids to provide c/s-fused fiveand six-membered cyclic homoallylic alcohols. The excellent diastereoand enantioselectivity and the fact that the reaction proceeds at room temperature in the absence of any additives make the process highly practical.
Original language | English |
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Pages (from-to) | 1047-1050 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 10 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2008 Mar 20 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry