TY - JOUR
T1 - Electron microscopy observations of the Au nanorods and Au nanorod/SiO2 nanocapsules
AU - Nakashima, Kouichi
AU - Inose, Tomoya
AU - Oikawa, Takahiro
AU - Tokunaga, Masayuki
AU - Hatoyama, Keiichiro
AU - Kakihana, Masato
AU - Gonda, Kohsuke
AU - Kobayashi, Yoshio
N1 - Funding Information:
This work was performed under the Research Program of the ?Dynamic Alliance for Open Innovation Bridging Human, Environment and Materials? in the ?Network Joint Research Center for Materials and Devices?. We are grateful to Dr. Manabu Shirai (Hitachi High-Tecnologies Co.) for STEM observation of 3D tomography. STEM observations (HD-2700, Hitachi High-Technologies Corporation) were performed at Technical Division, School of Engineering, Tohoku University.
Publisher Copyright:
© 2019 Japan Society of Powder and Powder Metallurgy.
PY - 2019
Y1 - 2019
N2 - An in-depth analysis of the morphology of Au nanorod/SiO2 nanocapsules was performed by scanning transmission electron microscopy (STEM) imaging, secondary electron (SE) imaging, bright-field (BF) imaging, and high-angle annular dark-field (HAADF) imaging. These detailed analyses and high X-ray computerized tomography (CT) values provided key information for the administration of Au nanorod/SiO2 nanocapsules into the blood of mice. Au, which is a heavy element, exhibits a high X-ray CT value. STEM images were recorded to clearly analyze the morphology of the Au nanorods and Au nanorod/SiO2 nanocapsules. The results obtained from SE images, BF images, and HAADF images revealed that Au nanorods are covered by SiO2 and that Au nanorod/ SiO2 nanocapsules are highly dispersed. Furthermore, 3D tomography reconstruction was performed by using STEM observation. Three-dimensional tomography reconstruction revealed a spatial structure and provided highly reliable information on the Au nanorod/SiO2 nanocapsules developed in this study.
AB - An in-depth analysis of the morphology of Au nanorod/SiO2 nanocapsules was performed by scanning transmission electron microscopy (STEM) imaging, secondary electron (SE) imaging, bright-field (BF) imaging, and high-angle annular dark-field (HAADF) imaging. These detailed analyses and high X-ray computerized tomography (CT) values provided key information for the administration of Au nanorod/SiO2 nanocapsules into the blood of mice. Au, which is a heavy element, exhibits a high X-ray CT value. STEM images were recorded to clearly analyze the morphology of the Au nanorods and Au nanorod/SiO2 nanocapsules. The results obtained from SE images, BF images, and HAADF images revealed that Au nanorods are covered by SiO2 and that Au nanorod/ SiO2 nanocapsules are highly dispersed. Furthermore, 3D tomography reconstruction was performed by using STEM observation. Three-dimensional tomography reconstruction revealed a spatial structure and provided highly reliable information on the Au nanorod/SiO2 nanocapsules developed in this study.
KW - 3D tomography
KW - Au nanorod
KW - Nanocapsule
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U2 - 10.2497/jjspm.66.210
DO - 10.2497/jjspm.66.210
M3 - Article
AN - SCOPUS:85069652614
VL - 66
SP - 210
EP - 214
JO - Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy
JF - Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy
SN - 0532-8799
IS - 5
ER -