Electron microscopy observations of the Au nanorods and Au nanorod/SiO2 nanocapsules

Kouichi Nakashima, Tomoya Inose, Takahiro Oikawa, Masayuki Tokunaga, Keiichiro Hatoyama, Masato Kakihana, Kohsuke Gonda, Yoshio Kobayashi

Research output: Contribution to journalArticlepeer-review

Abstract

An in-depth analysis of the morphology of Au nanorod/SiO2 nanocapsules was performed by scanning transmission electron microscopy (STEM) imaging, secondary electron (SE) imaging, bright-field (BF) imaging, and high-angle annular dark-field (HAADF) imaging. These detailed analyses and high X-ray computerized tomography (CT) values provided key information for the administration of Au nanorod/SiO2 nanocapsules into the blood of mice. Au, which is a heavy element, exhibits a high X-ray CT value. STEM images were recorded to clearly analyze the morphology of the Au nanorods and Au nanorod/SiO2 nanocapsules. The results obtained from SE images, BF images, and HAADF images revealed that Au nanorods are covered by SiO2 and that Au nanorod/ SiO2 nanocapsules are highly dispersed. Furthermore, 3D tomography reconstruction was performed by using STEM observation. Three-dimensional tomography reconstruction revealed a spatial structure and provided highly reliable information on the Au nanorod/SiO2 nanocapsules developed in this study.

Original languageEnglish
Pages (from-to)210-214
Number of pages5
JournalFuntai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy
Volume66
Issue number5
DOIs
Publication statusPublished - 2019

Keywords

  • 3D tomography
  • Au nanorod
  • Nanocapsule

ASJC Scopus subject areas

  • Mechanical Engineering
  • Industrial and Manufacturing Engineering
  • Metals and Alloys
  • Materials Chemistry

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