Electrochemical hydrogel lithography of calcium-alginate hydrogels for cell culture

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25 Citations (Scopus)


Here we propose a novel electrochemical lithography methodology for fabricating calcium-alginate hydrogels having controlled shapes. We separated the chambers for Ca2+ production and gel formation with alginate with a semipermeable membrane. Ca2+ formed in the production chamber permeated through the membrane to fabricate a gel structure on the membrane in the gel formation chamber. When the calcium-alginate hydrogels were modified with collagen, HepG2 cells proliferated on the hydrogels. These results show that electrochemical hydrogel lithography is useful for cell culture.

Original languageEnglish
Article number744
Issue number9
Publication statusPublished - 2016 Sep


  • Calcium-alginate hydrogel
  • Cell culture
  • Electrochemical hydrogel lithography
  • Electrodeposition

ASJC Scopus subject areas

  • Materials Science(all)


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