Electrochemical DNA sensors: From nanoconstruction to biosensing

Haixin Chang, Ying Wang, Jinghong Li

    Research output: Contribution to journalReview articlepeer-review

    13 Citations (Scopus)


    Electrochemical DNA sensors have been increasingly fascinating due to high sensitivity, specificity, portability and integrated compatibilities with microelectronics. Numerous strategies have been developed to design electrochemical DNA sensors with high sensitivity and selectivity. In this review, we will focus on the efforts toward sensitive electrochemical DNA sensing based on nanomaterials including metal nanoparticles, magnetic nanoparticles, semiconductor nanoparticles and carbon nanomaterials, especially carbon nanotubes. The potential application of the electrochemical DNA sensors in gene analysis, diagnosis, environmental and food safety monitoring will be briefly discussed. At the end of this review, we will give a brief outlook of the future challenges of electrochemical DNA sensors.

    Original languageEnglish
    Pages (from-to)506-517
    Number of pages12
    JournalCurrent Organic Chemistry
    Issue number4
    Publication statusPublished - 2011 Feb 10


    • Biosensing
    • DNA sensor
    • Electrochemical
    • Nanoconstruction

    ASJC Scopus subject areas

    • Organic Chemistry


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