TY - JOUR
T1 - Electrochemical DNA sensors
T2 - From nanoconstruction to biosensing
AU - Chang, Haixin
AU - Wang, Ying
AU - Li, Jinghong
PY - 2011/2/10
Y1 - 2011/2/10
N2 - Electrochemical DNA sensors have been increasingly fascinating due to high sensitivity, specificity, portability and integrated compatibilities with microelectronics. Numerous strategies have been developed to design electrochemical DNA sensors with high sensitivity and selectivity. In this review, we will focus on the efforts toward sensitive electrochemical DNA sensing based on nanomaterials including metal nanoparticles, magnetic nanoparticles, semiconductor nanoparticles and carbon nanomaterials, especially carbon nanotubes. The potential application of the electrochemical DNA sensors in gene analysis, diagnosis, environmental and food safety monitoring will be briefly discussed. At the end of this review, we will give a brief outlook of the future challenges of electrochemical DNA sensors.
AB - Electrochemical DNA sensors have been increasingly fascinating due to high sensitivity, specificity, portability and integrated compatibilities with microelectronics. Numerous strategies have been developed to design electrochemical DNA sensors with high sensitivity and selectivity. In this review, we will focus on the efforts toward sensitive electrochemical DNA sensing based on nanomaterials including metal nanoparticles, magnetic nanoparticles, semiconductor nanoparticles and carbon nanomaterials, especially carbon nanotubes. The potential application of the electrochemical DNA sensors in gene analysis, diagnosis, environmental and food safety monitoring will be briefly discussed. At the end of this review, we will give a brief outlook of the future challenges of electrochemical DNA sensors.
KW - Biosensing
KW - DNA sensor
KW - Electrochemical
KW - Nanoconstruction
UR - http://www.scopus.com/inward/record.url?scp=79551656474&partnerID=8YFLogxK
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U2 - 10.2174/138527211794474500
DO - 10.2174/138527211794474500
M3 - Review article
AN - SCOPUS:79551656474
VL - 15
SP - 506
EP - 517
JO - Current Organic Chemistry
JF - Current Organic Chemistry
SN - 1385-2728
IS - 4
ER -