Electrochemical approach to pattern proteins and cells within microchannels

Hirokazu Kaji, Masahiko Hashimoto, Kazuto Tsukidate, Tomokazu Matsue, Matsuhiko Nishizawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The use of microfluidic system is a trend in diagnostic assays and bioreactors based on the protein and cellular engineering. In the development of such devices, it would be essentially required to pattern proteins and cells within microchannels just prior to the use of the devices, since such delicate biomaterials exhibit the lower stability against desiccation, oxidation and heat. We have developed a microfluidic device which enables the real-time immobilization of proteins and cells within the microchannels using electrochemical means. This technique is easily applicable to the ordinary microfluidic systems, opening new possibilities for the microchannel-based bioassays.

Original languageEnglish
Title of host publicationMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
Subtitle of host publication9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherTransducer Research Foundation
Pages1309-1311
Number of pages3
ISBN (Print)0974361119, 9780974361116
Publication statusPublished - 2005 Jan 1
Event9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States
Duration: 2005 Oct 92005 Oct 13

Publication series

NameMicro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Volume1

Other

Other9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
Country/TerritoryUnited States
CityBoston, MA
Period05/10/905/10/13

Keywords

  • Cell patterning
  • Electrochemical method
  • Microchannel
  • Protein patterning

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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