Efficient thermal lens nanoparticle detection in a flow-focusing microfluidic device

Satomi Yamaoka, Yui Kataoka, Yuto Kazama, Yusaku Fujii, Akihide Hibara

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


A flow-focusing microfluidic device was fabricated for thermal lens nanoparticle detection. In this device, sample flow was first sandwiched by lateral z-axis sheath flows, and then by horizontal xy-plane sheath flows. The three-dimensional flow focus was visualized using an aqueous dye solution. Subsequently, 500-nm-sized red polystyrene particles were individually detected by the thermal lens detection method. When 1 μL of sample solution containing 300 particles/μL was passed through the thermal lens detection point, 255 ± 20 peaks corresponding to particles were observed.

Original languageEnglish
Pages (from-to)581-586
Number of pages6
JournalSensors and Actuators, B: Chemical
Publication statusPublished - 2016 Jun 2
Externally publishedYes


  • Flow focus
  • Microfluidics
  • Nanoparticle
  • Polydimethylsiloxane
  • Thermal lens

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry


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