Abstract
Exposure of 3-(tetrahydro-2-furyl)-3-trimethylsilylpropanoic acids and 3-(2-trimethylsilylmethyltetrahydro-2-furyl)propanoic acids to trifluoroacetic anhydride allows intramolecular acylative ring-opening reaction to give the corresponding eight-membered lactones in moderate to good yields.
Original language | English |
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Pages (from-to) | 1757-1759 |
Number of pages | 3 |
Journal | Synlett |
Issue number | 11 |
Publication status | Published - 1999 Jan 1 |
Externally published | Yes |
Keywords
- Acyloxonium ion
- Eight-membered lactones
- Octalactin analogs
- Ring enlargement
- Silicon compounds
ASJC Scopus subject areas
- Organic Chemistry