TY - JOUR
T1 - Efficient method for synthesis of angucyclinone antibiotics via gold-catalyzed intramolecular [4 + 2] benzannulation
T2 - Enantioselective total synthesis of (+)-ochromycinone and (+)-rubiginone B2
AU - Sato, Kenichiro
AU - Asao, Naoki
AU - Yamamoto, Yoshinori
PY - 2005/10/28
Y1 - 2005/10/28
N2 - An efficient synthetic approach to angucyclinone antibiotics, (+)-ochromycinone and (+)-rubiginone B2, is reported. The key step involves the facile formation of 2,3-dihydrophenantren-4(1H)-one skeleton, an important framework of angucyclinone natural products, by using gold-catalyzed intramolecular [4 + 2] benzannulation reaction.
AB - An efficient synthetic approach to angucyclinone antibiotics, (+)-ochromycinone and (+)-rubiginone B2, is reported. The key step involves the facile formation of 2,3-dihydrophenantren-4(1H)-one skeleton, an important framework of angucyclinone natural products, by using gold-catalyzed intramolecular [4 + 2] benzannulation reaction.
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U2 - 10.1021/jo051444m
DO - 10.1021/jo051444m
M3 - Article
C2 - 16238336
AN - SCOPUS:27444438651
VL - 70
SP - 8977
EP - 8981
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
SN - 0022-3263
IS - 22
ER -