Efficient entry to the pyrroloquinoline core of Martinella alkaloids via novel base-catalyzed Mukaiyama-Mannich reaction

Shuhei Ikeda, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

An efficient enantiocontrolled entry to Martinella alkaloids was achieved based on the unexpected discovery that a catalytic amount of KH/dicyclohexyl-18-crown-6 induced an intramolecular Mukaiyama-Mannich reaction of imine 3, leading to a cascade sequence involving a novel silyl group migration to furnish the pyrroloquinoline core 6.

Original languageEnglish
Pages (from-to)962-963
Number of pages2
JournalChemistry Letters
Volume37
Issue number9
DOIs
Publication statusPublished - 2008 Sep 5

ASJC Scopus subject areas

  • Chemistry(all)

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