Efficient dehydration of aldoximes to nitriles catalyzed by a Lewis acid ionic liquid

Mizuki Nakajima, Kun Kyo, Nobuhisa Kobayashi, Quanxi Bao, Daisuke Tomida, Chiaki Yokoyama

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

A Lewis acid ionic liquid, 1-[4-(chlorosulfonyl)butyl]-3-methylimidazolium chlorosulfate ([CBMIm]SO3Cl), with Lewis acid sites in both the anion and cation was synthesized. This was demonstrated to be an efficient catalyst for dehydration of aldoximes to nitriles. An unexpected self-induced phase separation of the reaction mixture was observed when the reaction was carried out in acetonitrile. This could be attributed to the hydrolysis of [CBMIm]SO3Cl to regenerate 1-(4-sulfobutyl)-3-methylimidazolium hydrogensulfate ([SBMIm]HSO4), which was the Brønsted precursor of [CBMIm]SO3Cl.

Original languageEnglish
Pages (from-to)396-397
Number of pages2
JournalChemistry Letters
Volume40
Issue number4
DOIs
Publication statusPublished - 2011 Mar 24

ASJC Scopus subject areas

  • Chemistry(all)

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