Abstract
A method for the synthesis of triazole-linked DNA oligomers has been revisited to incorporate a reliable protective group and linker for solid-phase synthesis. The new solid-phase synthesis allowed the preparation of oligomers with the efficiency of elongation reaching over 90%.
Original language | English |
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Pages (from-to) | 868-870 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 53 |
Issue number | 7 |
DOIs | |
Publication status | Published - 2012 Feb 15 |
Externally published | Yes |
Keywords
- DNA
- Oligonucleotides
- Protection
- Solid-phase synthesis
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry