Effects on implant element heating characteristics by blood flow of the human body for soft-heating hyperthermia

Kota Yokomatsu, Tetsuya Takura, Fumihiro Sato, Tadakuni Sato, Hidetoshi Matsuki, Toshiaki Yanada

Research output: Contribution to journalArticlepeer-review

Abstract

Hyperthermia is one of cancer therapies that necrotize tumor by heat. There are several types of hyperthermia corresponding to its way of heating. We have researched the Soft-Heating method, which uses heating elements composed of a thermosensitive magnetic material coated Au. These elements can generate heat effectively in high frequency magnetic field. Moreover, the temperature of the element does not rise higher than the Curie point of thermosensitive magnetic material because this material can’t concentrate magnetic flux at the Curie point or above. Therefore, we can conduct treatment without measuring the temperature inside the body. We have confirmed the inhibitory effect on a mouse tumor by Soft-Heating method. However, blood flow of the human body differs from that of a mouse so treatment can be incomplete. We report the results of numerical analysis on heating characteristics and effective layout of the elements considering blood flow of human.

Original languageEnglish
Pages (from-to)O-507-O-508
JournalTransactions of Japanese Society for Medical and Biological Engineering
Volume52
DOIs
Publication statusPublished - 2014 Aug 17

Keywords

  • Blood flow
  • Heating element
  • Hyperthermia
  • Soft-heating method

ASJC Scopus subject areas

  • Biomedical Engineering

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