Effects of triazole derivatives on strigolactone levels and growth retardation in rice

Shinsaku Ito, Mikihisa Umehara, Atsushi Hanada, Nobutaka Kitahata, Hiroki Hayase, Shinjiro Yamaguchi, Tadao Asami

    Research output: Contribution to journalArticlepeer-review

    23 Citations (Scopus)

    Abstract

    We previously discovered a lead compound for strigolactone (SL) biosynthesis inhibitors, TIS13 (2,2-dimethyl-7-phenoxy-4-(1H-1,2,4-triazol-1-yl)heptan-3-ol). Here, we carried out a structure-activity relationship study of TIS13 to discover more potent and specific SL biosynthesis inhibitor because TIS13 has a severe side effect at high concentrations, including retardation of the growth of rice seedlings. TIS108, a new TIS13 derivative, was found to be a more specific SL biosynthesis inhibitor than TIS13. Treatment of rice seedlings with TIS108 reduced SL levels in both roots and root exudates in a concentration-dependent manner and did not reduce plant height. In addition, root exudates of TIS108-treated rice seedlings stimulated Striga germination less than those of control plants. These results suggest that TIS108 has a potential to be applied in the control of root parasitic weeds germination.

    Original languageEnglish
    Article numbere21723
    JournalPloS one
    Volume6
    Issue number7
    DOIs
    Publication statusPublished - 2011

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)
    • Agricultural and Biological Sciences(all)
    • General

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