TY - JOUR
T1 - Effects of transdiagnostic group treatment for sleep disturbances in adult attention-deficit/hyperactivity disorders and autistic spectrum disorder
T2 - a pilot study
AU - Ishii, Miho
AU - Ito, Wakako
AU - Karube, Yuki
AU - Ogawa, Yuko
AU - Tagawa, Anna
AU - Maeda, Shunta
AU - Sato, Hideki
AU - Takahashi, Toru
AU - Inomata, Natsumi
AU - Narisawa, Hajime
AU - Takaesu, Yoshikazu
AU - Watanabe, Koichiro
AU - Okajima, Isa
N1 - Funding Information:
This work was partially supported by JSPS KAKENHI grant numbers 16K04388.
Funding Information:
The authors declare no conflict of interest. However, I.O. has received grants from NEC Solution Innovators and personal fees from Otsuka Pharmaceutical, Merck Sharp & Dohme, Eisai, and Takeda Pharmaceuticals for projects unrelated to the submitted work. Y.T. has received lecture fees from Otsuka Pharmaceutical, Meiji Seika Pharma, Eli Lilly, Eisai, Mitsubishi Tanabe Pharma, MSD, and Yoshitomi Pharmaceutical, and research funding from Otsuka Pharmaceutical, Meiji Seika Pharma, MSD, and Eisai.
Publisher Copyright:
© 2021, The Author(s).
PY - 2022/4
Y1 - 2022/4
N2 - Although adult patients with attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) often have sleep problems, few studies have verified the effect of a psychological approach specific to sleep–wake rhythms on these sleep disturbances. Therefore, the aim of this pilot study was to develop a trans-diagnostic approach with sleep scheduling and regularity of sleep duration as core modules, and to examine the effect of the intervention in adult ADHD and/or ASD subjects with sleep disturbances. This was a within-group pilot study. Ten patients with adult ADHD and/or ASD with sleep disturbances (10 males, age: 27.4 ± 5.6 years) took part in a 90-min weekly group intervention for 5 weeks. All participants were assessed on scales for sleep complaints, anxiety, depression, and symptoms of ADHD and ASD before and after the intervention, and at 3-month follow-up. The results showed that the intervention significantly improved sleep disturbances at post-intervention (p = 0.003, d = 1.30, 95% CI 0.31–2.28) and at the 3-month follow-up (p = 0.035, d = 0.41, 95% CI − 0.48 to 1.30). In addition, attention switching for ASD symptoms was significantly reduced post-intervention (p = 0.031, d = 1.16, 95% CI 0.19–2.13). This is the first pilot study of a trans-diagnostic group approach for adult ADHD and/or ASD with sleep disturbances. The intervention primarily led to an improvement of sleep disturbances, followed by improvement of disease-specific symptoms in adult subjects with ADHD and ASD.
AB - Although adult patients with attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) often have sleep problems, few studies have verified the effect of a psychological approach specific to sleep–wake rhythms on these sleep disturbances. Therefore, the aim of this pilot study was to develop a trans-diagnostic approach with sleep scheduling and regularity of sleep duration as core modules, and to examine the effect of the intervention in adult ADHD and/or ASD subjects with sleep disturbances. This was a within-group pilot study. Ten patients with adult ADHD and/or ASD with sleep disturbances (10 males, age: 27.4 ± 5.6 years) took part in a 90-min weekly group intervention for 5 weeks. All participants were assessed on scales for sleep complaints, anxiety, depression, and symptoms of ADHD and ASD before and after the intervention, and at 3-month follow-up. The results showed that the intervention significantly improved sleep disturbances at post-intervention (p = 0.003, d = 1.30, 95% CI 0.31–2.28) and at the 3-month follow-up (p = 0.035, d = 0.41, 95% CI − 0.48 to 1.30). In addition, attention switching for ASD symptoms was significantly reduced post-intervention (p = 0.031, d = 1.16, 95% CI 0.19–2.13). This is the first pilot study of a trans-diagnostic group approach for adult ADHD and/or ASD with sleep disturbances. The intervention primarily led to an improvement of sleep disturbances, followed by improvement of disease-specific symptoms in adult subjects with ADHD and ASD.
KW - Anxiety
KW - Attention switching
KW - Attention-deficit hyperactivity disorder
KW - Autism spectrum disorder
KW - Cognitive behavioral therapy
KW - Sleep–wake rhythms
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U2 - 10.1007/s41105-021-00351-8
DO - 10.1007/s41105-021-00351-8
M3 - Article
AN - SCOPUS:85118847036
SN - 1446-9235
VL - 20
SP - 173
EP - 180
JO - Sleep and Biological Rhythms
JF - Sleep and Biological Rhythms
IS - 2
ER -