Abstract
A layer-by-layer deposition technique was employed for fabricating choline biosensors using chloline oxidase (ChOx) and polycations such as poly(ethyleneimine) (PEI) and poly(diallyldimethylammonium chloride) (PDDA). A platinum electrode was coated with ChOx/PEI or ChOx/PDDA thin film to prepare amperometric choline sensors. The amperometric response of the sensors depended significantly on the type of the polycations. The ChOx/PDDA film suppressed the permeation of choline, resulting in a lower response than that of the ChOx/PEI film-based sensors. The results were rationalized based on the different chemical structures of the polycationic materials.
| Original language | English |
|---|---|
| Pages (from-to) | 433-435 |
| Number of pages | 3 |
| Journal | Materials Science and Engineering C |
| Volume | 25 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2005 Jun 1 |
Keywords
- Choline oxidase
- Choline sensor
- Layer-by-layer deposition
- PDDA (poly(diallyldimethylammonium chloride))
- PEI (poly(ethyleneimine))
ASJC Scopus subject areas
- Materials Science(all)
- Condensed Matter Physics
- Mechanics of Materials
- Mechanical Engineering
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Cite this
Shi, H., Song, Z., Huang, J., Yang, Y., Zhao, Z., Anzai, J. I., Osa, T., & Chen, Q. (2005). Effects of the type of polycation on the amperometric response of choline biosensors prepared by a layer-by-layer deposition technique. Materials Science and Engineering C, 25(4), 433-435. https://doi.org/10.1016/j.msec.2004.11.001