Effects of the type of polycation on the amperometric response of choline biosensors prepared by a layer-by-layer deposition technique

Haibin Shi, Zhao Song, Jiadong Huang, Yu Yang, Zixia Zhao, Jun Ichi Anzai, Tetsuo Osa, Qiang Chen

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A layer-by-layer deposition technique was employed for fabricating choline biosensors using chloline oxidase (ChOx) and polycations such as poly(ethyleneimine) (PEI) and poly(diallyldimethylammonium chloride) (PDDA). A platinum electrode was coated with ChOx/PEI or ChOx/PDDA thin film to prepare amperometric choline sensors. The amperometric response of the sensors depended significantly on the type of the polycations. The ChOx/PDDA film suppressed the permeation of choline, resulting in a lower response than that of the ChOx/PEI film-based sensors. The results were rationalized based on the different chemical structures of the polycationic materials.

Original languageEnglish
Pages (from-to)433-435
Number of pages3
JournalMaterials Science and Engineering C
Volume25
Issue number4
DOIs
Publication statusPublished - 2005 Jun 1

Keywords

  • Choline oxidase
  • Choline sensor
  • Layer-by-layer deposition
  • PDDA (poly(diallyldimethylammonium chloride))
  • PEI (poly(ethyleneimine))

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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