Effects of recombination on hitchhiking diversity in the brassica self-incompatibility locus complex

Shohei Takuno, Ryo Fujimoto, Tetsu Sugimura, Keiichi Sato, Shunsuke Okamoto, Shao Ling Zhang, Takeshi Nishio

    Research output: Contribution to journalArticlepeer-review

    32 Citations (Scopus)

    Abstract

    In self-incompatibility, a number of S haplotypes are maintained by frequency-dependent selection, which results in trans-specific S haplotypes. The region of several kilobases (∼40-60 kb) from SP6 to SP2, including self-incompatibility-related genes and some adjacent genes in Brassica rapa, has high nucleotide diversity due to the hitchhiking effect, and therefore we call this region the "S-locus complex." Recombination in the S-locus complex is considered to be suppressed. We sequenced regions of >50 kb of the S-locus complex of three S haplotypes in B. rapa and found higher nucleotide diversity in intergenic regions than in coding regions. Two highly similar regions of >10 kb were found between BrS-8 and BrS-46. Phylogenetic analysis using trans-specific S haplotypes (called interspecific pairs) of B. rapa and B. oleracea suggested that recombination reduced the nucleotide diversity in these two regions and that the genes not involved in self-incompatibility in the S-locus complex and the kinase domain, but not the S domain, of SRK have also experienced recombination. Recombination may reduce hitchhiking diversity in the S-locus complex, whereas the region from the S domain to SP11 would disfavor recombination.

    Original languageEnglish
    Pages (from-to)949-958
    Number of pages10
    JournalGenetics
    Volume177
    Issue number2
    DOIs
    Publication statusPublished - 2007 Oct

    ASJC Scopus subject areas

    • Genetics

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