Effects of pulsatile flow pattern and each stage of pressure increasing, constant and decreasing, respectively upon inelastic deformation of blood vessel

A. Toshimitsu Yokobori, Tsuneo Ohkuma, Toshihide Maeyama, Hiroshi Ohuchi, Takeo Yokobori

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    The aim of this study is to elucidate the relation of the inelastic expansive deformation of natural blood vessel and the degradation of elasticity to the time pattern of circulating pulsatile pressure flow. When pulsatile pressure amplitude (Δp = Pmax − Pmin) becomes smaller dueto Pmin increasing, the blood vessel is subject to creep deformation. In this sense, pulsating pressure will playa role in avoiding creep effect. Fluctuation o maximum pressure Pmax will induce the increase of inelastic deformation andthe decrease of rigidity of the blood vessel. The inelastic deformation and the decrease of rigidity in blood vessel is induced at the stage of pressure amplitude rising from a lower one to a higher, but not duringpressure amplitude (Δp) kept constant nor at the pressure amplitude decreasing stage. In order to reduce the degradation of mechanical properties of blood vessel, it may be effective to avoid the increase of Pmin and the variability of Pmax.

    Original languageEnglish
    Pages (from-to)233-241
    Number of pages9
    JournalBio-medical materials and engineering
    Volume1
    Issue number4
    DOIs
    Publication statusPublished - 1991

    Keywords

    • Blood vessel
    • Creep
    • Degradation
    • Inelastic deformation
    • Pulsatile pressure flow

    ASJC Scopus subject areas

    • Biomaterials
    • Biomedical Engineering

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