Effects of photo-induced graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on physical properties of cross-linked polyethylene in artificial hip joints

Masayuki Kyomoto, Toru Moro, Tomohiro Konno, Hiroaki Takadama, Hiroshi Kawaguchi, Yoshio Takatori, Kozo Nakamura, Noboru Yamawaki, Kazuhiko Ishihara

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47 Citations (Scopus)

Abstract

Osteolysis caused by wear particles from polyethylene in the artificial hip joints is a serious issue. We have used photo-induced radical graft polymerization to graft 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer onto the surface of cross-linked polyethylene (CLPE-g-MPC) in order to reduce friction and wear at the bearing surface of the joint. The physical and mechanical properties of CLPE and CLPE-g-MPC were not significantly different, expect that the friction coefficient of untreated CLPE cups was 0.0075, compared with 0.0009 for CLPE-g-MPC cup, an 88% reduction. After 3.0 × 10 6 cycles in the hip joint simulator test, we could not observe any wear of CLPE-g-MPC cups. We concluded that the advantage of photo-induced radical graft polymerization technique was that the grafted MPC polymer gave a high lubricity only on the surface and has no effect on the bulk properties of the CLPE substrate.

Original languageEnglish
Pages (from-to)1809-1815
Number of pages7
JournalJournal of Materials Science: Materials in Medicine
Volume18
Issue number9
DOIs
Publication statusPublished - 2007 Sep
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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