Effects of Perineural Capsaicin Treatment on Compound Action Potentials of Superior Laryngeal Nerve Afferents in Sevoflurane-Anesthetized Dogs

Tatsushi Mutoh; Arata Kanamaru; Kentaro Kojima; Ryohei Nishimura; Nobuo Sasaki; Hirokazu Tsubone

doi:10.1292/jvms.62.117

Effects of Perineural Capsaicin Treatment on Compound Action Potentials of Superior Laryngeal Nerve Afferents in Sevoflurane-Anesthetized Dogs

Tatsushi Mutoh, Arata Kanamaru, Kentaro Kojima, Ryohei Nishimura, Nobuo Sasaki, Hirokazu Tsubone

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Effects of perineural capsaicin (CAPS) treatment on compound action potentials of the superior laryngeal nerve (SLN) afferents were studied in 6 sevoflurane-anesthetized dogs. Perineural CAPS (100 μg/ml) to the bilateral SLNs reduced (P<0.01) the peak and integral amplitudes of the C-wave of the compound action potential. By contrast, the perineural CAPS had no effect on the A-wave component (P>0.05). Removal of the perineural CAPS recovered the C-wave to pretreatment level. The perineural CAPS treatment selectively blocks C-wave compound action potentials of the SLN afferents, providing a useful tool for studies of laryngeal C-fibers in respiratory physiology.

Original language	English
Pages (from-to)	117-120
Number of pages	4
Journal	Journal of Veterinary Medical Science
Volume	62
Issue number	1
DOIs	https://doi.org/10.1292/jvms.62.117
Publication status	Published - 2000 Jan
Externally published	Yes

Keywords

Canine
Conduction velocity
Laryngeal C-fiber

ASJC Scopus subject areas

veterinary(all)

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10.1292/jvms.62.117

Cite this

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title = "Effects of Perineural Capsaicin Treatment on Compound Action Potentials of Superior Laryngeal Nerve Afferents in Sevoflurane-Anesthetized Dogs",

abstract = "Effects of perineural capsaicin (CAPS) treatment on compound action potentials of the superior laryngeal nerve (SLN) afferents were studied in 6 sevoflurane-anesthetized dogs. Perineural CAPS (100 μg/ml) to the bilateral SLNs reduced (P<0.01) the peak and integral amplitudes of the C-wave of the compound action potential. By contrast, the perineural CAPS had no effect on the A-wave component (P>0.05). Removal of the perineural CAPS recovered the C-wave to pretreatment level. The perineural CAPS treatment selectively blocks C-wave compound action potentials of the SLN afferents, providing a useful tool for studies of laryngeal C-fibers in respiratory physiology.",

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AU - Mutoh, Tatsushi

AU - Kanamaru, Arata

AU - Kojima, Kentaro

AU - Nishimura, Ryohei

AU - Sasaki, Nobuo

AU - Tsubone, Hirokazu

PY - 2000/1

Y1 - 2000/1

N2 - Effects of perineural capsaicin (CAPS) treatment on compound action potentials of the superior laryngeal nerve (SLN) afferents were studied in 6 sevoflurane-anesthetized dogs. Perineural CAPS (100 μg/ml) to the bilateral SLNs reduced (P<0.01) the peak and integral amplitudes of the C-wave of the compound action potential. By contrast, the perineural CAPS had no effect on the A-wave component (P>0.05). Removal of the perineural CAPS recovered the C-wave to pretreatment level. The perineural CAPS treatment selectively blocks C-wave compound action potentials of the SLN afferents, providing a useful tool for studies of laryngeal C-fibers in respiratory physiology.

AB - Effects of perineural capsaicin (CAPS) treatment on compound action potentials of the superior laryngeal nerve (SLN) afferents were studied in 6 sevoflurane-anesthetized dogs. Perineural CAPS (100 μg/ml) to the bilateral SLNs reduced (P<0.01) the peak and integral amplitudes of the C-wave of the compound action potential. By contrast, the perineural CAPS had no effect on the A-wave component (P>0.05). Removal of the perineural CAPS recovered the C-wave to pretreatment level. The perineural CAPS treatment selectively blocks C-wave compound action potentials of the SLN afferents, providing a useful tool for studies of laryngeal C-fibers in respiratory physiology.

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Effects of Perineural Capsaicin Treatment on Compound Action Potentials of Superior Laryngeal Nerve Afferents in Sevoflurane-Anesthetized Dogs

Abstract

Keywords

ASJC Scopus subject areas

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