Effects of Perineural Capsaicin Treatment on Compound Action Potentials of Superior Laryngeal Nerve Afferents in Sevoflurane-Anesthetized Dogs

Tatsushi Mutoh, Arata Kanamaru, Kentaro Kojima, Ryohei Nishimura, Nobuo Sasaki, Hirokazu Tsubone

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Effects of perineural capsaicin (CAPS) treatment on compound action potentials of the superior laryngeal nerve (SLN) afferents were studied in 6 sevoflurane-anesthetized dogs. Perineural CAPS (100 μg/ml) to the bilateral SLNs reduced (P<0.01) the peak and integral amplitudes of the C-wave of the compound action potential. By contrast, the perineural CAPS had no effect on the A-wave component (P>0.05). Removal of the perineural CAPS recovered the C-wave to pretreatment level. The perineural CAPS treatment selectively blocks C-wave compound action potentials of the SLN afferents, providing a useful tool for studies of laryngeal C-fibers in respiratory physiology.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalJournal of Veterinary Medical Science
Volume62
Issue number1
DOIs
Publication statusPublished - 2000 Jan

Keywords

  • Canine
  • Conduction velocity
  • Laryngeal C-fiber

ASJC Scopus subject areas

  • veterinary(all)

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