Effects of pastes containing ion-releasing particles on dentin remineralization

Masahiro Iijima, Rina Ishikawa, Kyotaro Kawaguchi, Shuichi Ito, Takashi Saito, Itaru Mizoguchi

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


We investigated the effects of the weekly application of pastes containing a surface reaction-type pre-reacted glass-ionomer (S-PRG. filler on dentin remineralization. Human dentin blocks were demineralized and polished using pastes containing S-PRG filler (0, 5, and 30%., and then immersed in remineralizing solution for 1 month. Nanoindentation testing was carried out during the immersion period, and the dentin surfaces were examined using scanning electron microscopy. A nano-hydroxyapatite-containing paste was used for comparison. Immersion in demineralization solution had a marked negative effect on the mechanical properties in all specimens. The mechanical properties of specimens polished with S-PRG filler-containing pastes recovered significantly after immersion in remineralization solution for 1 month compared with the other specimens. After remineralization, the open dentinal tubules were filled with a remineralization layer in specimens polished with S-PRG filler-containing and nano-hydroxyapatite-containing pastes. S-PRG filler-containing pastes can aid dentin remineralization.

Original languageEnglish
Pages (from-to)271-277
Number of pages7
JournalDental materials journal
Issue number2
Publication statusPublished - 2019
Externally publishedYes


  • Dentin remineralization
  • Nanoindentation
  • Professional tooth polishing

ASJC Scopus subject areas

  • Ceramics and Composites
  • Dentistry(all)


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