Effects of oscillation on the arteries measured by arterial impedance during left ventricular assistance

Shinichi Kobayashi, Naoki Ohwada, Tomoyuki Yambe, Syunsuke Nanka, Shinichi Nitta, Takeo Fukuju, Tadayoshi Hongou, Hiroyuki Hashimoto

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Oscillating blood flow has effects on the arteries similar to the effects of pulsatile blood flow at lower frequencies. Alternating-current theory is useful to study the pulse in the circulatory system. Arterial impedance is a good index to estimate the frequency characteristics of the artery. In this study, total vascular resistance and arterial impedance were studied in animal experiments during left ventricular assistance. A centrifugal pump was used for comparison with a VFP (vibrating-flow pump). Left ventricular assistance was performed in animal experiments using goats. Total vascular resistance and arterial impedance were studied to estimate the frequency characteristics of the artery. Total vascular resistance during steady flow assistance decreased compared with that during nonassistance. Arterial walls were extended by the blood flow assistance at steady flow. The resistance during oscillating blood flow was different at each driving frequency, showing the frequency dependency, or pulse effect, of the arterial system under nonsteady flow. Arterial impedance was also studied during oscillating blood flow and showed a slight increase at a driving frequency of 25 or 30 Hz. These fluctuations in impedance are influenced by the reflection of the pulse. Arterial impedance should be taken into consideration when analyzing pulsatile blood flow because the pulse reflection may have some effects on the arterial wall. Some variation of blood pressure and blood flow might be necessary for stable support with artificial circulatory assistance.

Original languageEnglish
Pages (from-to)8-12
Number of pages5
JournalJournal of Artificial Organs
Volume2
Issue number1
DOIs
Publication statusPublished - 1999 Dec 1

Keywords

  • Arterial impedance
  • Left ventricular assistance
  • Oscillating blood flow
  • Pulse reflection

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering
  • Cardiology and Cardiovascular Medicine

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