Effects of menthol on the triggering of the swallowing reflex in elderly patients with dysphagia

Takae Ebihara, Satoru Ebihara, Aya Watando, Tatsuma Okazaki, Masanori Asada, Takashi Ohrui, Mutsuo Yamaya, Hiroyuki Arai

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Aims: To investigate the effect of menthol on swallowing reflex sensitivity in elderly patients with dysphagia. Methods and results: The swallowing reflex sensitivity of institutionalized elderly patients was evaluated as a latent time of swallowing reflex (LTSR), induced by the injection of 1 ml solution into the pharynx. LTSR was significantly shortened in a concentration-dependent manner, from 13.8 s [95% confidence interval (CI) 11.1, 16.5] by distilled water to 9.4 s (95% CI 7.1. 11.8) by 10-2m menthol. Conclusion: Using menthol with elderly patients with dysphagia may improve the sensitivity of their swallowing reflex, resulting in prevention of aspiration pneumonia.

Original languageEnglish
Pages (from-to)369-371
Number of pages3
JournalBritish journal of clinical pharmacology
Volume62
Issue number3
DOIs
Publication statusPublished - 2006 Sep 1

Keywords

  • Dysphagia
  • Elderly
  • Menthol
  • Swallowing reflex

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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