Effects of Japanese torreya (Torreya nucifera) seed oil on lipid metabolism in rats

Yasushi Endo, Yuko Osada, Fumiko Kimura, Kenshiro Fujimoto

    Research output: Contribution to journalArticle

    19 Citations (Scopus)

    Abstract

    Objective: We investigated effects of Japanese torreya (Torreya nucifera) seed oil containing non-methylene-interrupted polyunsaturated fatty acid of all-cis-5,11,14-eicosatrienoic acid (sciadonic acid) on rat lipid metabolism. Methods: Male Sprague-Dawley rats were fed the experimental diets based on AIN-93 containing 10% corn, soybean, or torreya oil for 4 wk. Blood and tissues were recovered from each rat, and concentrations of triacylglycerol, cholesterol, and phospholipid in plasma and liver were determined by enzymatic assays. Moreover, fatty acid composition was analyzed for triacylglycerol, cholesterol ester, and phospholipid isolated from plasma and liver lipids by gas liquid chromatography. Results: Plasma triacylglycerol level in rats fed torreya oil was lower than that in rats fed corn or soybean oil, although there were no significant differences in plasma cholesterol and phospholipid levels in all rats. Liver triacylglycerol level was also lower in rats fed torreya oil, whereas liver cholesterol and phospholipid levers were same for all rats. ω-3 Polyunsaturated fatty acids such as 22:6 (ω-3) were lower in plasma and liver lipids of torreya and corn oil groups, whereas ω-6 polyunsaturated fatty acids such as 22:4 (ω-6) and 22:5 (ω-6) were higher. Considerable amounts of sciadonic acid were detected in cholesterol ester, triacylglycerol, and phospholipid in plasma and liver of rats fed torreya oil. Conclusion: These observations suggest that torreya seed oil can modify lipid metabolism, resulting in lower triacylglycerol levels in plasma and liver of rats.

    Original languageEnglish
    Pages (from-to)553-558
    Number of pages6
    JournalNutrition
    Volume22
    Issue number5
    DOIs
    Publication statusPublished - 2006 May 1

    Keywords

    • Eicosatrienoic acid
    • Lipid metabolism
    • Non-methylene-interrupted polyunsaturated fatty acid
    • Sciadonic acid
    • Torreya nucifera
    • Triacylglycerol

    ASJC Scopus subject areas

    • Endocrinology, Diabetes and Metabolism
    • Nutrition and Dietetics

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