Effects of indigo carmine intravenous injection on noninvasive and continuous total hemoglobin measurement

Tsuyoshi Isosu, Tomohiko Satoh, Rieko Oishi, Tsuyoshi Imaizumi, Takahiro Hakozaki, Shinju Obara, Yukihiro Ikegami, Shin Kurosawa, Masahiro Murakawa

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    The effects of an intravenous injection of indigo carmine on noninvasive and continuous total hemoglobin (SpHb) measurement were retrospectively evaluated. The subjects were 21 patients who underwent elective gynecologic surgery under general anesthesia. During surgery, 5 mL of 0.4 % indigo carmine was intravenously injected, and subsequent changes in SpHb concentrations were evaluated. The results demonstrate that the pre-injection SpHb level was 10 g/dL, and the minimum post-injection SpHb level was 8.3 g/dL. The amount of decrease was 1.8 g/dL. The time to reach the minimum value was 4 min, and the time to return to the pre-injection value was 15 min. The decrease in SpHb was greater in the group with a perfusion index (PI) < 1.4 than in the group with a PI > 1.4. The assessment of SpHb after an intravenous injection of indigo carmine necessitates caution.

    Original languageEnglish
    Pages (from-to)313-316
    Number of pages4
    JournalJournal of Clinical Monitoring and Computing
    Volume30
    Issue number3
    DOIs
    Publication statusPublished - 2016 Jun 1

    Keywords

    • CO-oximetry
    • Indigo carmine
    • Perfusion index
    • SpHb

    ASJC Scopus subject areas

    • Health Informatics
    • Critical Care and Intensive Care Medicine
    • Anesthesiology and Pain Medicine

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