Effects of feeding and cholecystokinin-octapeptide (CCK-8) on the somatotropic axis of goats around weaning

Y. Kobayashi, M. Onodera, M. Yoshida, P. Guilloteau, K. Katoh, Y. Obara

    Research output: Contribution to journalArticle

    Abstract

    Post-prandial plasma GH concentrations significantly increased prior to weaning but did not change or decrease after weaning in goats. We hypothesized that this phenomenon was induced by changes in the digestive function or in gastrointestinal hormone secretion at weaning. We therefore gave intravenous administrations of CCK-8 in order to establish whether or not it stimulated GH secretion. The administration in pre-weaned animals increased the GH level, but not ghrelin levels, which were significantly greater than in post-weaned animals. These results suggest that the regulation of somatotropic axis after feeding may be stimulated by peripherally secreted CCK.

    Original languageEnglish
    Pages (from-to)421-424
    Number of pages4
    JournalJournal of Animal and Feed Sciences
    Volume13
    Issue numberSUPPL. 1
    DOIs
    Publication statusPublished - 2004 Jan 1

    Keywords

    • Cholecystokinin
    • Feeding
    • Ghrelin
    • Growth hormone
    • Weaning

    ASJC Scopus subject areas

    • Food Science
    • Animal Science and Zoology

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