Effects of endocrine therapy on the primary lesion in patients with prostatic cancer ; evaluation with Gd-dynamic subtraction MRI

T. Yoshizako, Y. Watanabe, M. Dohke, A. Okumura, K. Amoh, T. Hayashi, M. Yasui, S. Nakashita, J. Nakanishi, Y. Dodo, K. Ogura, Y. Arai

Research output: Contribution to journalArticlepeer-review

Abstract

The effects of endocrine therapy on prostate cancer were assessed by using Gd-dynamic subtraction MRI (DSMRI). The 36 lesions showed early enhancement before therapy were treated with endocrine therapy. The criteria used for the assessment of therapeutic effect was ; the degree of early enhancement could decrease with the viability of cancer reduced by treatment. According to this criteria, the sensitivity, specificity, and accuracy were 35.7% (5/14), 81.8% (18/22), and 58.3% (21/36). In conclusion, interval decrease of early enhancement could be a indicator of therapeutic effect.

Original languageEnglish
Pages (from-to)1141-1145
Number of pages5
JournalJapanese Journal of Clinical Radiology
Volume45
Issue number10
Publication statusPublished - 2000 Jan 1

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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