TY - JOUR
T1 - Effects of biomaterials on cell adhesion of human periodontal ligament fibroblasts and fibronectin adsorption
AU - Iwamatsu-Kobayashi, Y.
AU - Nishihara, D.
AU - Hirata, M.
AU - Kindaichi, K.
AU - Komatsu, M.
N1 - Funding Information:
This work was supported by Grant-in Aid for Encouragement of Young Scientists (No. 14771049, 14771050) from Japan Society for the Promotion of Science, Japan.
PY - 2005/9
Y1 - 2005/9
N2 - Effects of biomaterials such as machined pure titanium (Ti), poly lactic acid (PLA), poly lactic-co-glycolic acid (PLGA) and collagen on adhesion of human periodontal ligament fibroblasts (HPLF) and fibronectin (FN) adsorption were examined. The numbers of adhered cells cultured on Ti, PLA and PLGA were significantly lower than those on control and collagen-coated disks in the early culture period. At this period, FN adsorption on Ti, PLA and PLGA was higher than control and collagen-coated disks. FN adsorption became comparable on all disks when cell numbers on Ti, PLA and PLGA caught up with those on control and collagen-coated disks after long-term culture. It is suggested that HPLF may adhere to biomaterials controlling FN adsorption.
AB - Effects of biomaterials such as machined pure titanium (Ti), poly lactic acid (PLA), poly lactic-co-glycolic acid (PLGA) and collagen on adhesion of human periodontal ligament fibroblasts (HPLF) and fibronectin (FN) adsorption were examined. The numbers of adhered cells cultured on Ti, PLA and PLGA were significantly lower than those on control and collagen-coated disks in the early culture period. At this period, FN adsorption on Ti, PLA and PLGA was higher than control and collagen-coated disks. FN adsorption became comparable on all disks when cell numbers on Ti, PLA and PLGA caught up with those on control and collagen-coated disks after long-term culture. It is suggested that HPLF may adhere to biomaterials controlling FN adsorption.
KW - Biomaterial
KW - Fibronectin
KW - Periodontal ligament fibroblast
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U2 - 10.1016/j.ics.2005.06.055
DO - 10.1016/j.ics.2005.06.055
M3 - Review article
AN - SCOPUS:33646442500
VL - 1284
SP - 334
EP - 335
JO - International Congress Series
JF - International Congress Series
SN - 0531-5131
ER -