TY - JOUR
T1 - Effects of Adrenergic Agonists and Antagonists on Immediate Cutaneous Reactions in Bronchial Asthma
AU - Ohmi, Tetsuhiro
AU - Mue, Suetsugu
AU - Takahashi, Makoto
AU - Shibahara, Shigeki
AU - Yamauchi, Kohei
AU - Tamura, Gen
AU - Fujimoto, Satoru
AU - Takishima, Tamotsu
AU - Chu Chen, Hwei
PY - 1979
Y1 - 1979
N2 - Ohmi, T., Mue, S., Takahashi, M., Shibahara, S., Yamauchi, K., Tamura, G., Fujimoto, S., Chen, H.C. and Takishima, T. Effects of Adrenergic Agonists and Antagonists on Immediate Cutaneous Reactions in Bronchial Asthma. Tohoku J. exp. Med., 1979, 127 (2), p.197-198 — Asthmatic patients who showed an allergic skin reaction to house-dust antigen (HD) were injected intradermally with a mixture of HD and a various dose of isoproterenol (Isopr) or propranolol (Propr). In some cases Isopr clearly suppressed the formation of the wheal, but in some others Isopr did not much affect the allergic skin reaction. Also Propr increased markedly the skin reaction of some patients, or had little effect on it. The sensitivity of the skin of asthmatic patients to these drugs was closely correlated with the general response of the patients to adrenaline, such as changes in heart rate, diastolic blood pressure, blood glucose level, and blood triglyceride level. — adrenergic drugs; skin and systemic response; asthma.
AB - Ohmi, T., Mue, S., Takahashi, M., Shibahara, S., Yamauchi, K., Tamura, G., Fujimoto, S., Chen, H.C. and Takishima, T. Effects of Adrenergic Agonists and Antagonists on Immediate Cutaneous Reactions in Bronchial Asthma. Tohoku J. exp. Med., 1979, 127 (2), p.197-198 — Asthmatic patients who showed an allergic skin reaction to house-dust antigen (HD) were injected intradermally with a mixture of HD and a various dose of isoproterenol (Isopr) or propranolol (Propr). In some cases Isopr clearly suppressed the formation of the wheal, but in some others Isopr did not much affect the allergic skin reaction. Also Propr increased markedly the skin reaction of some patients, or had little effect on it. The sensitivity of the skin of asthmatic patients to these drugs was closely correlated with the general response of the patients to adrenaline, such as changes in heart rate, diastolic blood pressure, blood glucose level, and blood triglyceride level. — adrenergic drugs; skin and systemic response; asthma.
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U2 - 10.1620/tjem.127.197
DO - 10.1620/tjem.127.197
M3 - Article
C2 - 32645
AN - SCOPUS:0018742283
VL - 127
SP - 197
EP - 198
JO - Tohoku Journal of Experimental Medicine
JF - Tohoku Journal of Experimental Medicine
SN - 0040-8727
IS - 2
ER -