Abstract
Normal doughnuts or lots of little ones? Among four stereoisomers of a tetravalent polyamine, the isomer pictured was the most potent at inducing DNA compaction, whereby the DNA molecules adopted a unique morphology of minitoroid clusters. The nonchiral polyamine spermine induced the formation of typical, larger toroidal structures.
| Original language | English |
|---|---|
| Pages (from-to) | 3712-3716 |
| Number of pages | 5 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 52 |
| Issue number | 13 |
| DOIs | |
| Publication status | Published - 2013 Mar 25 |
Keywords
- DNA structures
- amines
- chirality
- fluorescence microscopy
- single-molecule studies
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
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Yoshikawa, Y., Umezawa, N., Imamura, Y., Kanbe, T., Kato, N., Yoshikawa, K., Imanaka, T., & Higuchi, T. (2013). Effective chiral discrimination of tetravalent polyamines on the compaction of single DNA molecules. Angewandte Chemie - International Edition, 52(13), 3712-3716. https://doi.org/10.1002/anie.201209144