Abstract
Normal doughnuts or lots of little ones? Among four stereoisomers of a tetravalent polyamine, the isomer pictured was the most potent at inducing DNA compaction, whereby the DNA molecules adopted a unique morphology of minitoroid clusters. The nonchiral polyamine spermine induced the formation of typical, larger toroidal structures.
Original language | English |
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Pages (from-to) | 3712-3716 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 52 |
Issue number | 13 |
DOIs | |
Publication status | Published - 2013 Mar 25 |
Externally published | Yes |
Keywords
- DNA structures
- amines
- chirality
- fluorescence microscopy
- single-molecule studies
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)