Effect of underwear made from MEDIELE® on skin barrier function of atopic dermatitis patients in winter season

Maki Ozawa, Ikuko Numata, Akiko Watabe, Hiroko Koizumi, Ai Memezawa, Katsuko Kikuchi, Setsuya Aiba

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We compared the effects of underwear made from ethylene-vinyl alcohol copolymer fiber (MEDIELE®) with those made from cotton on skin condition of atopic dermatitis patients in winter season. This was a randomized, single-blind, crossover study in which the subjects consecutively wore MEDIELE® and cotton underwear for 4 weeks each. Local SCORAD, skin conductance and transepidermal water loss (TEWL) were measured on the scapular region. There was no difference in local SCORAD and the skin conductance values. An increase of the TEWL value was observed at the endpoint of wearing cotton underwear. On the other hand, the TEWL value was maintained at the same level during the period of wearing MEDIELE® underwear. Therefore, we concluded the underwear made from MEDIELE® was useful in maintaining skin barrier function of atopic dermatitis patients in winter season.

Original languageEnglish
Pages (from-to)475-481
Number of pages7
JournalSkin Research
Volume7
Issue number4
Publication statusPublished - 2008 Aug

Keywords

  • Atopic dermatitis
  • Barrier function
  • Stratum corneum
  • TEWL
  • Underwear

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

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    Ozawa, M., Numata, I., Watabe, A., Koizumi, H., Memezawa, A., Kikuchi, K., & Aiba, S. (2008). Effect of underwear made from MEDIELE® on skin barrier function of atopic dermatitis patients in winter season. Skin Research, 7(4), 475-481.