Effect of treatment position on normal tissue dose in different clinical target volumes in external beam radiotherapy for prostate cancer

Takahiro Kato, Yasunori Obata, Nobukazu Fuwa, Hideki Shimada, Noriyuki Kadoya

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To quantitatively assess the differences between supine and prone positions on normal tissue dose in different clinical target volumes (CTVs) in irradiation of prostate cancer. Materials and Method: Eighteen patients with prostate cancer underwent treatment planning CT scans in the supine and prone positions. The prostate only (PO) and prostate plus seminal vesicles (PS) were delineated as CTVs. A six-field plan was generated and compared concerning the rectum and bladder dose-volume histogram in both treatment positions in each of the respective CTVs. The distance between the PS and rectum in both treatment positions was also measured. Results: In some cases, the distance between the seminal vesicles and rectum changed by more than 20 mm in the transition from supine to prone, although the change in distance was about 5 mm in many cases. Significant differences in rectal V90 were observed only in PS between the supine and prone positions (p=0.0015). However, significant differences in bladder V90 were not observed in both CTVs between the supine and prone positions. Conclusion: The effect of rectal dose reduction using the prone position in irradiation of prostate cancer depends on the range of CTV.

Original languageEnglish
Pages (from-to)71-76
Number of pages6
JournalJournal of JASTRO
Volume21
Issue number2
Publication statusPublished - 2009 Jun 1

Keywords

  • Prone position
  • Prostate cancer
  • Radiotherapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Oncology

Fingerprint Dive into the research topics of 'Effect of treatment position on normal tissue dose in different clinical target volumes in external beam radiotherapy for prostate cancer'. Together they form a unique fingerprint.

Cite this