Effect of the Japanese diet during pregnancy and lactation or post-weaning on the risk of metabolic syndrome in offspring

Haruna Ishikawa, Xiaoxu Guo, Saeko Sugawara, Yui Iwagaki, Kazushi Yamamoto, Tsuyoshi Tsuduki

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

We examined the effects on offspring of ingestion of the 1975 Japanese diet during pregnancy and lactation and after weaning in mice. Pregnant dams were divided into groups that were fed the Japanese diet or a control diet and raised until offspring were weaned. The offspring after weaning were further divided into groups that were raised on the Japanese diet or the control diet. Ingestion of the Japanese diet after weaning suppressed accumulation of visceral fat in offspring, and reduced the amount of lipids in serum and liver. This effect was weakened if the Japanese diet was only ingested during pregnancy and lactation. Therefore, it was suggested that ingestion of the Japanese diet of mothers during pregnancy and lactation weakens the lipid accumulation inhibitory effect of the Japanese diet in children.

Original languageEnglish
Pages (from-to)515-524
Number of pages10
JournalBioscience, Biotechnology and Biochemistry
Volume82
Issue number3
DOIs
Publication statusPublished - 2018

Keywords

  • 1975 Japanese diet
  • Japanese diet
  • Lactation
  • Offspring
  • Pregnancy

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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