TY - JOUR
T1 - Effect of Silk Fibroin Concentration on the Properties of Polyethylene Glycol Dimethacrylates for Digital Light Processing Printing
AU - Egawa, Satoshi
AU - Kurita, Hiroki
AU - Kanno, Teruyoshi
AU - Narita, Fumio
N1 - Funding Information:
The authors greatly acknowledge the support of this work by the Japan Society for the Promotion of Science (JSPS), Grant‐in‐Aid for Challenging Research (Pioneering) under grant no. 20K20430.
Publisher Copyright:
© 2021 Wiley-VCH GmbH.
PY - 2021/9
Y1 - 2021/9
N2 - Attempts are made to use silk fibroin (SF), which is a protein produced by the silkworm, as a scaffold material in the field of regenerative medicine due to its high biocompatibility. Herein, the concentration of SF is varied and mixed with the light-curing resin polyethylene glycol dimethacrylate (PEGDMA) to create a bioink, and the hydrogel is printed by digital light processing (DLP) 3D printing. Then, to investigate the properties of the printed hydrogel, scanning electron microscope (SEM) observation, swelling behavior measurement, and compression testing are conducted. The properties of hydrogels depend on the concentration of SF, and this result indicates that it is possible to create a scaffold with properties suitable for some tissue by controlling the amount of SF.
AB - Attempts are made to use silk fibroin (SF), which is a protein produced by the silkworm, as a scaffold material in the field of regenerative medicine due to its high biocompatibility. Herein, the concentration of SF is varied and mixed with the light-curing resin polyethylene glycol dimethacrylate (PEGDMA) to create a bioink, and the hydrogel is printed by digital light processing (DLP) 3D printing. Then, to investigate the properties of the printed hydrogel, scanning electron microscope (SEM) observation, swelling behavior measurement, and compression testing are conducted. The properties of hydrogels depend on the concentration of SF, and this result indicates that it is possible to create a scaffold with properties suitable for some tissue by controlling the amount of SF.
KW - 3D printing
KW - biocomposites
KW - mechanical properties
KW - resins
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U2 - 10.1002/adem.202100487
DO - 10.1002/adem.202100487
M3 - Article
AN - SCOPUS:85110937595
VL - 23
JO - Advanced Engineering Materials
JF - Advanced Engineering Materials
SN - 1438-1656
IS - 9
M1 - 2100487
ER -