Effect of osmolarity and viscosity on the motility of pathogenic and saprophytic Leptospira

Kyosuke Takabe, Shuichi Nakamura, Masamichi Ashihara, Seishi Kudo

Research output: Contribution to journalComment/debatepeer-review

9 Citations (Scopus)

Abstract

The motility of bacteria is an important factor in their infectivity. In this study, the motility of Leptospira, a member of the spirochete family that causes a zoonotic disease known as leptospirosis, was analyzed in different viscous or osmotic conditions. Motility assays revealed that both pathogenic and saprophytic strains increase their swimming speeds with increasing viscosity. However, only pathogenic Leptospira interrogans maintained vigorous motility near physiological osmotic conditions. This suggests that active motility in physiological conditions is advantageous when Leptospira enters hosts and when it migrates toward target tissues.

Original languageEnglish
Pages (from-to)236-239
Number of pages4
JournalMICROBIOLOGY and IMMUNOLOGY
Volume57
Issue number3
DOIs
Publication statusPublished - 2013 Mar 1

Keywords

  • Leptospira
  • Motility
  • Osmolarity
  • Viscosity

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Virology

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