TY - GEN
T1 - Effect of organic polymer addition on the microstructure of magnetite-polymer hybrid
AU - Kuwahara, Y.
AU - Miyazaki, T.
AU - Kawashita, M.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - This study is concerning hybrid materials composed of the magnetite and the organic polymer such as dextran. They are useful for hyperthermia of cancer. In the preparation of this material, chemical structure or molecular weight of the added polymer is expected to affect ionic interaction between polymer and iron salts, and consequently the grain size and morphology of the prepared magnetite core. Therefore, we have synthesized magnetite-polymer hybrids using various polymers. Various polymers were dissolved in iron (II) chloride aqueous solution, and then NaOH aqueous solution was added to this mixed solution. As a result, in the case of neutral and cationic polymer crystalline magnetite was precipitated in the hybrid. On the other hand, in the case of anionic polyacrylic acid, lepidocrocite was precipitated rather than magnetite. It is known that the magnetite formation progresses through intermediate Fe(OH) 2 formation and oxidation of the Fe(OH)2 by dissolved O2. Therefore it is considered that tight ionic interaction is constructed between the iron ions and the carboxyl group in the polyacrylic acid to form a complex, and the Fe(OH)2 formation is inhibited. When the hybrid was prepared by addition of NaOH aqueous solution to iron (II) chloride solution, and subsequent addition of the different polymers, magnetite formation was not inhibited irrespective of kind of polymer. The present results indicate that crystalline structure of the magnetite phase in magnetite-polymer hybrid is strongly affected by the chemical structure of polymer additives or the order of addition.
AB - This study is concerning hybrid materials composed of the magnetite and the organic polymer such as dextran. They are useful for hyperthermia of cancer. In the preparation of this material, chemical structure or molecular weight of the added polymer is expected to affect ionic interaction between polymer and iron salts, and consequently the grain size and morphology of the prepared magnetite core. Therefore, we have synthesized magnetite-polymer hybrids using various polymers. Various polymers were dissolved in iron (II) chloride aqueous solution, and then NaOH aqueous solution was added to this mixed solution. As a result, in the case of neutral and cationic polymer crystalline magnetite was precipitated in the hybrid. On the other hand, in the case of anionic polyacrylic acid, lepidocrocite was precipitated rather than magnetite. It is known that the magnetite formation progresses through intermediate Fe(OH) 2 formation and oxidation of the Fe(OH)2 by dissolved O2. Therefore it is considered that tight ionic interaction is constructed between the iron ions and the carboxyl group in the polyacrylic acid to form a complex, and the Fe(OH)2 formation is inhibited. When the hybrid was prepared by addition of NaOH aqueous solution to iron (II) chloride solution, and subsequent addition of the different polymers, magnetite formation was not inhibited irrespective of kind of polymer. The present results indicate that crystalline structure of the magnetite phase in magnetite-polymer hybrid is strongly affected by the chemical structure of polymer additives or the order of addition.
KW - Hyperthermia
KW - Magnetite
KW - Organic polymer
KW - Organic-inorganic hybrid
UR - http://www.scopus.com/inward/record.url?scp=84871297938&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871297938&partnerID=8YFLogxK
U2 - 10.4028/www.scientific.net/KEM.529-530.453
DO - 10.4028/www.scientific.net/KEM.529-530.453
M3 - Conference contribution
AN - SCOPUS:84871297938
SN - 9783037855171
T3 - Key Engineering Materials
SP - 453
EP - 456
BT - Bioceramics 24
PB - Trans Tech Publications Ltd
T2 - 24th Symposium and Annual Meeting of International Society for Ceramics in Medicine, ISCM 2012
Y2 - 21 October 2012 through 24 October 2012
ER -