Effect of nitrous oxide on spike activity during epilepsy surgery

Y. Sato, K. Sato, H. Shamoto, M. Kato, T. Yoshimoto

    Research output: Contribution to journalArticlepeer-review

    13 Citations (Scopus)

    Abstract

    There are controversies over the effect of nitous oxide on the electrocorticograms in patients with epilepsy. To clarify the effect of nitrous oxide on electrocorticograms, spike activities were compared with and without nitrous oxide under neuroleptoanesthesia in 10 patients with intractable epilepsy during surgery. Spikes decreased with nitous oxide significantly (P < 0.01) and disappeared in 3 cases. We conclude that discontinuation of nitrous oxide should be taken into consideration during electrocorticographic monitoring in epilepsy surgery.

    Original languageEnglish
    Pages (from-to)1213-1216
    Number of pages4
    JournalActa neurochirurgica
    Volume143
    Issue number12
    DOIs
    Publication statusPublished - 2001

    Keywords

    • Electrocorticogram
    • Epilepsy
    • Nitrous oxide

    ASJC Scopus subject areas

    • Surgery
    • Clinical Neurology

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