Effect of measurement error on ultrasonic-measurement-integrated simulation of blood flow in an aortic aneurysm

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Stresses due to blood flow on a blood vessel wall (hemodynamic stresses) are closely related to development and progression of circulatory diseases such as atherosclerosis and aneurysm. Therefore, for advanced diagnosis of circulatory diseases, accurate and detailed information of hemodynamics is necessary. To reproduce blood flow field, we have proposed ultrasonic- measurement-integrated (UMI) simulation, in which feedback signals are applied to the governing equations based on errors between ultrasonic measurement and numerical simulation at feedback points. Efficiency of the UMI simulation was shown by our previous numerical experiment dealing with a three-dimensional unsteady blood flow field in the descending aorta with an aneurysm. However, real ultrasonic measurement data inherently includes some errors. In this study, the effects of four major measurement errors, namely, errors due to Gaussian noise, aliasing, wall filter and lack of data, on computational accuracy of the UMI simulation were examined by a numerical experiment dealing with the blood flow field in an aortic aneurysm, the same as in our previous study. While solving the governing equations in UMI simulation, Gaussian noise did not work as an effective feedback signal, and, therefore, hardly influenced the computational result. In contrast, aliasing caused significant errors in the UMI simulation. By detecting significantly large feedback signals as a sign of aliasing and by replacing the measured Doppler velocity with the computational one, the computational accuracy of the UMI simulation was substantially improved. Effects of wall filter and lack of data especially appeared in diastole and in systole, respectively, but they were alleviated by not adding feedback signals where measured Doppler velocities were zero. Hence, UMI simulation can be performed with suppression of measurement errors.

Original languageEnglish
Title of host publication6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
Pages1652-1655
Number of pages4
DOIs
Publication statusPublished - 2010 Oct 22
Event6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech - Singapore, Singapore
Duration: 2010 Aug 12010 Aug 6

Publication series

NameIFMBE Proceedings
Volume31 IFMBE
ISSN (Print)1680-0737

Other

Other6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
CountrySingapore
CitySingapore
Period10/8/110/8/6

Keywords

  • Aneurysm
  • Bio-fluid mechanics
  • Computational fluid dynamics
  • Measurement-integrated simulation
  • Ultrasonic measurement

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

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  • Cite this

    Funamoto, K., Hayase, T., Saijo, Y., & Yambe, T. (2010). Effect of measurement error on ultrasonic-measurement-integrated simulation of blood flow in an aortic aneurysm. In 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech (pp. 1652-1655). (IFMBE Proceedings; Vol. 31 IFMBE). https://doi.org/10.1007/978-3-642-14515-5_420