Effect of Isoelectric point on enzyme immobilization property of magnetic apatite microcapsules encapsulating maghemite

Masaya Yamamoto, Takeshi Yabutsuka, Shigeomi Takai, Takeshi Yao

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

It is well-known that apatite has high affinity to many kinds of biomolecules. In this study, the authors aimed to develop the apatite microcapsules with both enzyme immobilization property by the bioaffinity of apatite and magnetism of core materials. The authors encapsulated maghemite particles, possesing ferrimagnetism, with apatite by attaching Apatite Nuclei on the surfaces of maghemite particles and subsequently immersing them in SBF. To evaluate performance of the microcapsules as enzyme immobilization carriers, the authors investigated enzyme immobilization property of the microcapsules fabricated by biomimetic method using Apatite Nuclei and SBF from the viewpoint of the difference of isoelectric point of the three-Types of enzymes.

Original languageEnglish
Title of host publicationBioceramics - 29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine
EditorsChristian Rey, Christele Combes, Christophe Drouet
PublisherTrans Tech Publications Ltd
Pages178-183
Number of pages6
ISBN (Print)9783035712209
DOIs
Publication statusPublished - 2017
Externally publishedYes
Event29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2017 - Toulouse, France
Duration: 2017 Oct 252017 Oct 27

Publication series

NameKey Engineering Materials
Volume758 KEM
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795

Other

Other29th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2017
CountryFrance
CityToulouse
Period17/10/2517/10/27

Keywords

  • Apatite Nuclei
  • Apatite microcapsules
  • Enzyme immobilization
  • Maghemite
  • Magnetic property

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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