TY - JOUR
T1 - Effect of ion species on apatite-forming ability of silicone elastomer substrates irradiated by cluster ion beams
AU - Kawashita, Masakazu
AU - Araki, Rei
AU - Takaoka, Gikan H.
N1 - Funding Information:
This study was partially supported by a Grant-in-Aid for Young Scientists (A), Funds for Promoting Science and Technology under the Program for Exploring Advanced Interdisciplinary Frontiers, the Ministry of Education, Culture, Sports, Science and Technology, Japan, Nippon Sheet Glass Foundation for Materials Science and Engineering, Japan, and the Nanotechnology Support Project of the Ministry of Education, Culture, Sports, Science and Technology, Japan.
PY - 2009/4/15
Y1 - 2009/4/15
N2 - Indwelling catheters made of silicone elastomers sometimes cause serious infections owing to their poor biocompatibility. It is believed that these infections can be prevented by coating the silicone surface with apatite, which has excellent biocompatibility. If the surface of the silicone elastomer is in advance modified to have an apatite-forming ability, apatite can be coated on the modified silicone surface by soaking it in an aqueous solution such as a simulated body fluid (SBF) supersaturated with respect to apatite. In this study, silicone substrates were irradiated by four types of ion beams (Ar cluster, Ar cluster and monomer (Ar CM), O2 cluster, and O2 cluster and monomer (O2 CM) ion beams) at an acceleration voltage of 7 kV and a dose of 1 × 1015 ions/cm2, and subsequently soaked in CaCl2 solution. The apatite-forming abilities of the substrates were examined using a metastable calcium phosphate solution whose ion concentration was 1.5 times that of SBF (1.5 SBF). Silicon oxide (SiOx) clusters were formed on the silicone surface and the hydrophilicity of the substrates was improved by the irradiation, irrespective of the ion species used. The irradiation with O2 CM ion beams resulted in the highest apatite-forming ability among the analyzed ion beams.
AB - Indwelling catheters made of silicone elastomers sometimes cause serious infections owing to their poor biocompatibility. It is believed that these infections can be prevented by coating the silicone surface with apatite, which has excellent biocompatibility. If the surface of the silicone elastomer is in advance modified to have an apatite-forming ability, apatite can be coated on the modified silicone surface by soaking it in an aqueous solution such as a simulated body fluid (SBF) supersaturated with respect to apatite. In this study, silicone substrates were irradiated by four types of ion beams (Ar cluster, Ar cluster and monomer (Ar CM), O2 cluster, and O2 cluster and monomer (O2 CM) ion beams) at an acceleration voltage of 7 kV and a dose of 1 × 1015 ions/cm2, and subsequently soaked in CaCl2 solution. The apatite-forming abilities of the substrates were examined using a metastable calcium phosphate solution whose ion concentration was 1.5 times that of SBF (1.5 SBF). Silicon oxide (SiOx) clusters were formed on the silicone surface and the hydrophilicity of the substrates was improved by the irradiation, irrespective of the ion species used. The irradiation with O2 CM ion beams resulted in the highest apatite-forming ability among the analyzed ion beams.
KW - Apatite
KW - Cluster ion beam
KW - Silicone
KW - Simulated body fluid
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U2 - 10.1016/j.mseb.2009.01.011
DO - 10.1016/j.mseb.2009.01.011
M3 - Article
AN - SCOPUS:67349219128
SN - 0921-5107
VL - 161
SP - 155
EP - 159
JO - Materials Science and Engineering B: Solid-State Materials for Advanced Technology
JF - Materials Science and Engineering B: Solid-State Materials for Advanced Technology
IS - 1-3
ER -