Effect of intra-arterial cisplatin on multiple liver metastases from rectal cancer associated with ulcerative colitis

Chikashi Shibata, Xue Lin Jin, Yuji Funayama, Kouhei Fukushima, Ken Ichi Takahashi, Akihiko Hashimoto, Munenori Nagao, Sho Haneda, Kazuhiro Watanabe, Seiki Matsuno, Iwao Sasaki, Hiroo Naito

Research output: Contribution to journalArticlepeer-review

Abstract

We report a patient with synchronous multiple liver metastases from rectal cancer associated with ulcerative colitis. Because the liver tumors were unresectable, we performed total proctocolectomy and hepatic intra-arterial cisplatin infusion with systemic oral administration of fluorouracil. A complete response was obtained. The patient is alive without sign of recurrence 5 years postoperatively. Hepatic intra-arterial administration of cisplatin should be considered in the treatment of unresectable liver metastases from colorectal cancer.

Original languageEnglish
Pages (from-to)57-61
Number of pages5
JournalTohoku Journal of Experimental Medicine
Volume202
Issue number1
DOIs
Publication statusPublished - 2004 Jan

Keywords

  • Cisplatin
  • Colitic cancer
  • Liver
  • Metastasis
  • Ulcerative colitis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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