Effect of ileo-jejunal transposition on intestinal adaptation after total colectomy in dogs.

I. Sasaki, T. Tuchiya, H. Naito, Y. Funayama, M. Toda, Y. Suzuki, T. Sato, A. Ohneda

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5 Citations (Scopus)

Abstract

The effect of ileo-jejunal transposition (IJT) on the intestinal adaptation after total colectomy was investigated in 4 mongrel dogs. Hyperenteroglucagonemia was observed in the IJT with colectomy group, especially in postprandial state. Obvious hyperplastic changes were observed in all part of the small intestinal mucosa in the colectomy with IJT group. However, there were no significant differences in body weight changes between the colectomy with IJT group and the colectomy group. Postprandial plasma gastrin levels were lower in the colectomy with IJT group compared to the control. These results suggest that IJT causes hyperenteroglucagonemia and intestinal mucosal hypertrophy in colectomized dogs. Enteroglucagon may have an inhibitory effect on postprandial gastrin release.

Original languageEnglish
Pages (from-to)419-428
Number of pages10
JournalTohoku Journal of Experimental Medicine
Volume151
Issue number4
Publication statusPublished - 1987 Apr

ASJC Scopus subject areas

  • Medicine(all)

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